Urolithin A 99% GRAS certificated Ingredients for Brain Health

Product Name:    Urolithin A Synonym Name:   3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one  CAS. Number:     1143-70-0 Molecular weight:  C13H8O4 Specifications:     Urolithin A 99% Appearance:      Beige to light yellow powder

Products Details

Urolithin A introduction

Urolithin A, also called 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one contains NLT 98.0% of Urolithin A (C13H8O4), calculated on the anhydrous basis. It’s a secondary metabolite of ellagic acid, a polyphenolic antioxidant that has anti-proliferative, anti-inflammatory,and anti-oxidant properties.

Specifications of Urolithin A

Urolithin A 99.0% HPLC

Benefits of Urolithin A

 Urolithin A decreases proliferation in ECC-1, and modulates estrogen receptor-regulated gene expression..  Urolithin A reduces inflammation and decreasing prostagelandine E2 and preventing protein levels in colonic mucosa.  Urolithin A induces mitophagy and mode-K intestinal cells in correlation withi improved fitness and extended lifespan.

Typical specification sheet of Urolithin A 99%

Analysis Items Specifications Methods
  1. NMR 
1H NMR confirms to product structure.
  1. LC-MS
LC-MS Conforms to molecular weight.
  1. HPLC
Retention time of the sample matches with the RS in HPLC purity test.
Physical Tests
Appearance Beige to light yellow powder Visual
Melting point 65~67℃ GB 617
Bulk density 0.30-0.60g/mL GB 5009.2
Moisture content ≤0.50% GB 5009.3
Residue on ignition ≤0.50% GB 5009.4
Active Ingredients Tests
Urolithin A Purity ≥98.00% HPLC
Max Single impurity ≤1.00% HPLC
Chemical Tests
Heavy Metals ≤10.00ppm GB 5009.74
Pb<Lead> ≤3.00ppm GB 5009.12
As<Inorganic arsenic> ≤2.00ppm GB 5009.11
Cd<Cadmium> ≤1.00ppm GB 5009.15
Hg<Total mercury> ≤0.10ppm GB 5009.17
Residue of Methanol ≤3,000ppm GB 5009.262
Residue of DMSO ≤5,000ppm GB 5009.262
Residue of Acetic Acid ≤5,000ppm GB 5009.262
Microbiological Tests
Total Bacterial Counts ≤1,000cfu/g GB 4789.2
Yeasts and Molds ≤100cfu/g GB 4789.15
Coliform group ≤1.0MPN/g GB 4789.3
Salmonella Negative in 10g GB 4789.4
* Conclusion: Conform to above specifications.
* Packaging: 20/25kg per fiber drum.
* Storage Condition: Preserve in well-closed, tight containers with temperature below 10℃.
* Shelf Life: 3 years when properly stored.

Application Cases

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